Systemically administered central nervous system drugs induced ocular side effects: a review
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چکیده
منابع مشابه
HYPERVITAMINOSIS A-INDUCED CENTRAL NERVOUS SYSTEM DEFECTS
In this investigation the effects of excess vitamin A administration during the early embryonic period were studied. Intramuscular injection of a single dose of 15000,20000 or 25000 IU/kg vitamin A to pregnant Balb/c strain mice on either day 7,8,9 or 10 of gestation (vaginal plug= day 0 of gestation) produced major malformations in the central nervous system (CNS) including exencephaly, h...
متن کاملOcular side-effects of drugs.
The eye may manifest side-effects from a wide variety of drugs used in the treatment of diseases of all systems of the body. Some of these side-effects, though undesirable, have to be accepted as unavoidable. The discovery of serious ocular defects arising in association with the long-term use in high dosage of such drugs as the antimalarials, the phenothiazines, and the steroid hormones has in...
متن کاملhypervitaminosis a-induced central nervous system defects
in this investigation the effects of excess vitamin a administration during the early embryonic period were studied. intramuscular injection of a single dose of 15000,20000 or 25000 iu/kg vitamin a to pregnant balb/c strain mice on either day 7,8,9 or 10 of gestation (vaginal plug= day 0 of gestation) produced major malformations in the central nervous system (cns) including exencephaly, hydroc...
متن کاملClinical Pharmacokinetics of Systemically Administered Antileishmanial Drugs
This review describes the pharmacokinetic properties of the systemically administered antileishmanial drugs pentavalent antimony, paromomycin, pentamidine, miltefosine and amphotericin B (AMB), including their absorption, distribution, metabolism and excretion and potential drug-drug interactions. This overview provides an understanding of their clinical pharmacokinetics, which could assist in ...
متن کاملMetronidazole-induced central nervous system toxicity: a systematic review.
OBJECTIVE To assess patient and medication factors that contribute to metronidazole toxicity. DATA SOURCES We searched PUBMED from 1965 through April 7, 2011, and performed a hand search of bibliographies. STUDY SELECTION Case reports or case series reporting metronidazole-induced central nervous toxicity. DATA EXTRACTION Two authors independently abstracted demographics, metronidazole in...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2021
ISSN: 2279-0780,2319-2003
DOI: 10.18203/2319-2003.ijbcp20212089